Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ZFPM1 antibody (Middle Region)

ZFPM1 Reactivity: Human, Rat, Cow WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779499
  • Target See all ZFPM1 Antibodies
    ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))
    Binding Specificity
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 26
    • 18
    • 17
    • 1
    • 1
    Human, Rat, Cow
    Host
    • 27
    • 1
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZFPM1 antibody is un-conjugated
    Application
    • 25
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PPPPPPGHAP APESPRPGSG SGSGPGLAPA RSPGPAADGP IDLSKKPRRP
    Predicted Reactivity
    Cow: 91%, Human: 100%, Rat: 83%
    Characteristics
    This is a rabbit polyclonal antibody against ZFPM1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ZFPM1
    Top Product
    Discover our top product ZFPM1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1006 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sugiyama, Tanaka, Kitajima, Zheng, Yen, Murotani, Yamatodani, Nakano: "Differential context-dependent effects of friend of GATA-1 (FOG-1) on mast-cell development and differentiation." in: Blood, Vol. 111, Issue 4, pp. 1924-32, (2008) (PubMed).

  • Target
    ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))
    Alternative Name
    ZFPM1 (ZFPM1 Products)
    Synonyms
    FOG antibody, FOG1 antibody, ZC2HC11A antibody, ZNF408 antibody, ZNF89A antibody, Fog1 antibody, Xfog antibody, fog antibody, fog-1 antibody, fog1 antibody, FOG-1 antibody, si:dkey-20g6.1 antibody, si:dkey-38l12.1 antibody, ZNF469 antibody, ZFPM1 antibody, zinc finger protein, FOG family member 1 antibody, zinc finger protein, multitype 1 antibody, zinc finger protein, FOG family member 1 L homeolog antibody, ZFPM1 antibody, Zfpm1 antibody, zfpm1.L antibody, zfpm1 antibody
    Background
    ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
    Alias Symbols: FOG, FOG1, ZNF408, ZNF89A
    Protein Interaction Partner: GSK3B, CTBP2, TRIM21, MTA1, RBBP4, Rb1, GATA1, GIPC1, TOP3B, GATA2,
    Protein Size: 1006
    Molecular Weight
    105 kDa
    Gene ID
    161882
    NCBI Accession
    NM_153813, NP_722520
    UniProt
    Q8IX07
You are here:
Support