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AES antibody (Middle Region)

AES Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779565
  • Target See all AES Antibodies
    AES (Amino-terminal Enhancer of Split (AES))
    Binding Specificity
    • 15
    • 11
    • 8
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 46
    • 13
    • 12
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 43
    • 2
    • 1
    Rabbit
    Clonality
    • 45
    • 1
    Polyclonal
    Conjugate
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AES antibody is un-conjugated
    Application
    • 28
    • 22
    • 13
    • 13
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    HKQAEIVKRL NGICAQVLPY LSQEHQQQVL GAIERAKQVT APELNSIIRQ
    Predicted Reactivity
    Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against AES. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human AES
    Top Product
    Discover our top product AES Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 264 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    AES (Amino-terminal Enhancer of Split (AES))
    Alternative Name
    AES (AES Products)
    Synonyms
    AES-1 antibody, AES-2 antibody, ESP1 antibody, GRG antibody, GRG5 antibody, TLE5 antibody, AL024115 antibody, Esp1 antibody, Grg antibody, Grg-5 antibody, Grg5 antibody, Tle5 antibody, zgc:64216 antibody, aes-1 antibody, aes-2 antibody, esp1 antibody, grg antibody, grg5 antibody, tle5 antibody, xgrg-5 antibody, AES antibody, amino-terminal enhancer of split antibody, amino-terminal enhancer of split S homeolog antibody, AES antibody, Aes antibody, aes antibody, aes.S antibody
    Background
    AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: AES-1, AES-2, ESP1, GRG, GRG5, TLE5
    Protein Interaction Partner: MFAP1, MBNL1, SMAD3, LMO2, LMO1, KRT31, DDX6, CRX, BYSL, BCL6, AES, AEN, CARD9, PARVG, LSM2, HOMEZ, MAGOHB, RNF31, VPS37C, C1orf109, OSGIN1, MED4, PRPF31, GORASP2, KANK2, LDOC1, MTUS2, DIP2A, NCDN, BAHD1, IKZF3, U2AF2, RBPMS, FRS3, NEK6, CALCOCO2, ABI2, T
    Protein Size: 264
    Molecular Weight
    29 kDa
    Gene ID
    166
    NCBI Accession
    NM_198969, NP_945320
    UniProt
    Q14CJ1
    Pathways
    WNT Signaling, SARS-CoV-2 Protein Interactome
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