CTBP1 antibody (C-Term)

Catalog No. ABIN2779662

Product Details anti-CTBP1 Antibody

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TGIPAAVEGI VPSAMSLSHG LPPVAHPPHA PSPGQTVKPE ADRDHASDQL

Predicted Reactivity: Dog: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CTBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CTBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 429 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CTBP1

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Alternative Name: CTBP1 (CTBP1 Products)

Synonyms: BARS antibody, CtBP1-L antibody, CtBP1-S antibody, CtBP3/BARS antibody, D4S115h antibody, D5H4S115 antibody, D5H4S115E antibody, 50-kDaBFA-inducedADP-ribosylatedsubstrate antibody, BARS-50 antibody, Bars antibody, wu:fi43a11 antibody, CtBP antibody, ctbp1-A antibody, xctbp1 antibody, bars antibody, CTBP1 antibody, C-terminal binding protein 1 antibody, C-terminal binding protein 1 L homeolog antibody, CTBP1 antibody, Ctbp1 antibody, ctbp1 antibody, ctbp1.L antibody

Background: CTBP1 binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Alias Symbols: BARS
Protein Interaction Partner: CTBP2, CTBP1, CRY2, NOL4L, FOXP2, DMRTB1, TSHZ3, BCAS3, PLCB1, CEP68, KLF12, IKZF1, NOL4, TGIF1, MAPK9, PRKAA1, HOXB5, TCF4, SNRPN, DGCR6, NRIP1, FUNDC1, LNX1, LCOR, RNF111, KLF3, IKZF2, RAI2, ZBTB18, ARNT2, ZEB2, PIAS2, CDC23, LCORL, MARCH10, SMAD6, UBC,
Protein Size: 429

Molecular Weight: 47 kDa

Gene ID: 1487

NCBI Accession: NM_001012614, NP_001012632

UniProt: Q7Z2Q5

Pathways: Retinoic Acid Receptor Signaling Pathway