GATA3 antibody (C-Term)

Catalog No. ABIN2779713

Product Details anti-GATA3 Antibody

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: RNRKMSSKSK KCKKVHDSLE DFPKNSSFNP AALSRHMSSL SHISPFSHSS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against GATA3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GATA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 443 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GATA3 antibody (ABIN2779713)

Kaminuma, Kitamura, Kitamura, Miyagishi, Taira, Yamamoto, Miura, Miyatake: "GATA-3 suppresses IFN-gamma promoter activity independently of binding to cis-regulatory elements." in: FEBS letters, Vol. 570, Issue 1-3, pp. 63-8, (2004) (PubMed).

Target Details for GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Alternative Name: GATA3 (GATA3 Products)

Background: Trans-acting T-cell specific transcription factor GATA-3 is a member of GATA family of transcription factors that regulates development of multiple tissues. It is an important transcription factor in regulating human Th2 cell differentiation in vivo.
Alias Symbols: HDR, HDRS
Protein Interaction Partner: PSMA3, FOXP3, USP21, UBC, SPI1, BRCA1, MYB, REPIN1, SP1, TBX21, HDAC5, HDAC4, HDAC3, RARB, MDM2, BMI1, MED1, ZFPM2, SATB1, TAL1, LMO1, LMO2, ETS2, ETS1,
Protein Size: 443

Molecular Weight: 48 kDa

Gene ID: 2625

NCBI Accession: NM_002051, NP_002042

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation