SND1 antibody (N-Term)

Catalog No. ABIN2779724

Product Details anti-SND1 Antibody

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SND1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LPDYYLVTVM LSGIKCPTFR READGSETPE PFAAEAKFFT ESRLLQRDVQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SND1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SND1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 885 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Alternative Name: SND1 (SND1 Products)

Background: SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN)-like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery
Alias Symbols: p100, TDRD11
Protein Interaction Partner: HUWE1, RAPGEF2, UBC, SUMO2, MDM2, LIN28A, SHFM1, DDX3X, EIF3CL, RPL35, RPS27, RPS26, RPS16, RPS11, RPS9, RPS6, RPS3A, RPS2, RPL23A, HNRNPU, TARDBP, UBD, RNU4-1, RNU5A-1, RNU6-1, PRPF8, RNU2-1, RNU1-1, G3BP1, VCAM1, MAK, ITGA4, FN1, CSNK2A1, SSR3, SRSF3, R
Protein Size: 885

Molecular Weight: 100 kDa

Gene ID: 27044

NCBI Accession: NM_014390, NP_055205

UniProt: Q7KZF4