HIPK2 antibody (Homeodomain Interacting Protein Kinase 2) (Middle Region)

Details for Product anti-HIPK2 Antibody No. ABIN2779735, Supplier: Log in to see
Antigen
  • HIPK2
  • cb1009
  • si:dkey-16j24.2
  • si:dkey-239k7.1
  • wu:fk56d12
  • pro0593
  • MGC146781
  • PRO0593
  • 1110014O20Rik
  • B230339E18Rik
  • Stank
  • PKM
  • homeodomain interacting protein kinase 2
  • serine/threonine protein kinase
  • HIPK2
  • hipk2
  • Hipk2
Alternatives
anti-Human HIPK2 antibody for Immunohistochemistry
Epitope
Middle Region
26
17
13
10
7
4
3
3
3
2
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
98
11
7
2
1
1
1
1
1
1
1
1
1
Host
Rabbit
85
13
Clonality
Polyclonal
Conjugate
This HIPK2 antibody is un-conjugated
8
8
8
8
8
4
Application
Immunohistochemistry (IHC), Western Blotting (WB)
64
61
35
16
14
4
4
3
3
1
Options
Supplier
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Supplier Product No.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of Human HIPK2
Blocking Peptide Blocking peptide for this product available: ABIN977995
Sequence MWSLGCVIAE LFLGWPLYPG ASEYDQIRYI SQTQGLPAEY LLSAGTKTTR
Predicted Reactivity Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 87%
Characteristics This is a rabbit polyclonal antibody against HIPK2. It was validated on Western Blot.
Purification Affinity Purified
Alternative Name HIPK2 (HIPK2 Antibody Abstract)
Background HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
Alias Symbols: DKFZp686K02111, FLJ23711, PRO0593
Protein Interaction Partner: UBC, TP53, SIAH2, XAF1, AATF, SUMO1, MDM2, AXIN1, SIAH1, MBP, DAXX, MKNK1, MECP2, ZBTB4, HIPK2, DCAF7, DYRK1B, MAP3K1, DYRK1A, FBXO3, CBX4, SUMO2, SUMO3, PML, PAX6, CHMP4B, SENP2, SENP1, UBE2I, HIST2H2BE, CXCL1, SIAH1P1, WSB1, MYBL2, MYBL1, NLK, MAP3K7, M
Protein Size: 1198
Molecular Weight 120 kDa
Gene ID 28996
NCBI Accession NM_022740, NP_073577
UniProt Q9H2X6
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Pathways Cell Division Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1198 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-Homeodomain Interacting Protein Kinase 2 (HIPK2) (Middle Region) antibody (ABIN2779735) anti-Homeodomain Interacting Protein Kinase 2 (HIPK2) (Middle Region) antibody
Product cited in: Upadhyay, Bhadauriya, Ganesh: "Heat shock modulates the subcellular localization, stability, and activity of HIPK2." in: Biochemical and biophysical research communications, Vol. 472, Issue 4, pp. 580-4, 2016 (PubMed).

Steinmann, Schulte, Beck, Chachra, Bujnicki, Klempnauer: "v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300." in: Oncogene, Vol. 28, Issue 26, pp. 2446-55, 2009 (PubMed).

Choi, Seo, Kim, Sung, Ahn, Park, Lee, Choi: "Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4682-9, 2008 (PubMed).

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