FOXH1 antibody (Middle Region)

Catalog No. ABIN2779837

Product Details anti-FOXH1 Antibody

Target: FOXH1 (Forkhead Box H1 (FOXH1))

Binding Specificity: Middle Region

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXH1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GPSSSSETPL WPLCSLPGPT IIEGESSQGE VIRPSPVTPD QGSWPLHLLE

Predicted Reactivity: Mouse: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against FOXH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse FOXH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 401 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOXH1

Target: FOXH1 (Forkhead Box H1 (FOXH1))

Alternative Name: FOXH1 (FOXH1 Products)

Synonyms: FOXH1 antibody, XFast-1 antibody, fast-1 antibody, fast1 antibody, foxh1a antibody, xfast1 antibody, xfoxh1 antibody, FAST-1 antibody, FAST1 antibody, Fast1 antibody, Fast2 antibody, fast-2 antibody, SUR antibody, fast antibody, fe26b06 antibody, schmalspur antibody, wu:fe26b06 antibody, wu:fi30c08 antibody, wu:fi32b01 antibody, forkhead box H1 antibody, forkhead box H1 L homeolog antibody, FOXH1 antibody, foxh1 antibody, Foxh1 antibody, foxh1.L antibody

Background: Foxh1 is a transcriptional activator. Foxh1 can recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3' and is required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Foxh1 forms a transcriptionally active complex containing FAST-1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Alias Symbols: Fast2
Protein Interaction Partner: Nkx2-5, Gsc, Smad2, Gtf2a1, Rxrg, Smad3, Alx4, Mef2c,
Protein Size: 401

Molecular Weight: 44 kDa

Gene ID: 14106

NCBI Accession: NM_007989, NP_032015

UniProt: O88621

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling