HHEX antibody (C-Term)

Catalog No. ABIN2779849

Product Details anti-HHEX Antibody

Target: HHEX (Hematopoietically Expressed Homeobox (HHEX))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HHEX antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SLDTSCEQGQ DLPSEQNKGA SLDRSQCSPS PASQEDPDSE ISEDSDQEVD

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 92%, Horse: 85%, Human: 86%, Mouse: 100%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against Hhex. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the c terminal region of mouse Hhex

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 271 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HHEX

Target: HHEX (Hematopoietically Expressed Homeobox (HHEX))

Alternative Name: Hhex (HHEX Products)

Synonyms: hhex antibody, Hex antibody, prh antibody, XHex antibody, hmph antibody, prhx antibody, tHex antibody, hox11l-pen antibody, HHEX antibody, hex antibody, hhex-A antibody, HEX antibody, HMPH antibody, HOX11L-PEN antibody, PRH antibody, PRHX antibody, Hex1 antibody, Hhex-rs2 antibody, Prh antibody, Prhx antibody, PROBOX antibody, Homeobox protein PRH antibody, hematopoietically expressed homeobox antibody, hematopoietically expressed homeobox L homeolog antibody, Bm1_31285 antibody, hhex antibody, HHEX antibody, Hex1 antibody, hhex.L antibody, Hhex antibody

Background: Hhex recognizes the DNA sequence 5'-ATTAA-3'. Hhex is a transcriptional repressor.It may play a role in hematopoietic differentiation.Hhex establishes anterior identity at two levels, acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.
Alias Symbols: Hex, Hhex-rs2, Prh, Prhx
Protein Interaction Partner: Sox10, Sox8, SRY, Sp7, Gtf2a1l, Jun, Fos,
Protein Size: 271

Molecular Weight: 30 kDa

Gene ID: 15242

NCBI Accession: NM_008245, NP_032271

UniProt: P43120