IRX3 antibody (N-Term)

Catalog No. ABIN2779862

Product Details anti-IRX3 Antibody

Target: IRX3 (Iroquois Homeobox 3 (IRX3))

Binding Specificity: N-Term

Reactivity: Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRX3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LGYQYIRPLY PPERPGAAGG GGGGSSAGGR SGPGAGASEL AASGSLSNVL

Predicted Reactivity: Cow: 86%, Dog: 86%, Mouse: 100%, Pig: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against IRX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 507 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-IRX3 antibody (ABIN2779862)

Sun, Hafler, Kaing, Kitada, Ligon, Widlund, Yuk, Stiles, Rowitch: "Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube." in: Developmental biology, Vol. 292, Issue 1, pp. 152-64, (2006) (PubMed).

Target Details for IRX3

Target: IRX3 (Iroquois Homeobox 3 (IRX3))

Alternative Name: IRX3 (IRX3 Products)

Synonyms: IRX-1 antibody, IRXB1 antibody, AI894186 antibody, iro3 antibody, irx3b antibody, xiro-3 antibody, xiro3 antibody, hm:zehn0543 antibody, id:ibd3380 antibody, irx3 antibody, wu:fk88a03 antibody, zgc:109805 antibody, wu:fb36a07 antibody, zgc:76885 antibody, ziro3b antibody, iroquois homeobox 3 antibody, Iroquois related homeobox 3 antibody, iroquois homeobox 3 L homeolog antibody, iroquois homeobox 3a antibody, iroquois homeobox 3b antibody, IRX3 antibody, Irx3 antibody, irx3.L antibody, irx3a antibody, irx3b antibody

Background: IRX3 is a member of the Iroquois homeobox gene family that encodes a protein known for its essential role in spinal cord development.
Alias Symbols: AI894186
Protein Size: 507

Molecular Weight: 56 kDa

Gene ID: 16373

NCBI Accession: NM_008393, NP_032419

UniProt: P81067

Pathways: Tube Formation