STAT1 antibody (N-Term)

Catalog No. ABIN2779897

Product Details anti-STAT1 Antibody

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QLQSWFTIVA ETLQQIRQQL KKLEELEQKF TYEPDPITKN KQVLSDRTFL

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 86%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against STAT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse STAT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 749 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAT1

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Alternative Name: STAT1 (STAT1 Products)

Synonyms: CANDF7 antibody, ISGF-3 antibody, STAT91 antibody, 2010005J02Rik antibody, AA408197 antibody, XStat1 antibody, STAT4 antibody, DD6G4-4 antibody, STAT antibody, STAT1 antibody, dZ182H3.3 antibody, si:by134g18.2 antibody, si:by51f19.1 antibody, si:dz182h3.3 antibody, si:dz199m19.1 antibody, si:dz73o4.2 antibody, stat1 antibody, signal transducer and activator of transcription 1 antibody, signal transducer and activator of transcription 1 L homeolog antibody, signal transducer and activator of transcription 1, 91kDa antibody, signal transducer and activator of transcription 4 antibody, signal transducer and activator of transcription 1a antibody, STAT1 antibody, Stat1 antibody, stat1.L antibody, stat4 antibody, stat1a antibody

Background: Stat1 is a member of the STAT family. It can form homodimers to modulate the transcriptional repression of PPARgamma2 in adipocytes
Alias Symbols: AA408197, 2010005J02Rik
Protein Interaction Partner: Isg15, Sumo1, Zfp467, Stat1, Fbxo2, Mapk1, Ubc, Btrc, Atf3, Pdlim2, Stat3, Mllt10, SMURF2, SMURF1, TGFBR1, SMAD4, ACVR1, Il6st, Gfap, S100b, Ifng, Tbx21,
Protein Size: 749

Molecular Weight: 82 kDa

Gene ID: 20846

NCBI Accession: NM_009283, NP_033309

UniProt: P42225

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events