NFAT1 antibody (N-Term)
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- Target See all NFAT1 Antibodies
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NFAT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MDVPEPQPDP DGGDGPGHEP GGSPQDELDF SILFDYDYLN PIEEEPIAHK
- Predicted Reactivity
- Cow: 86%, Dog: 82%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 79%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against NFATC2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse NFATC2
- Top Product
- Discover our top product NFAT1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 927 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells)." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 28, pp. 9641-6, (2010) (PubMed).
: "Phenotypic modulation of human urinary tract stroma-derived fibroblasts by transforming growth factor beta3." in: Urology, Vol. 76, Issue 2, pp. 509.e13-20, (2010) (PubMed).
: "
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Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells)." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 28, pp. 9641-6, (2010) (PubMed).
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- Target
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
- Alternative Name
- NFATC2 (NFAT1 Products)
- Synonyms
- NFATC2 antibody, AI607462 antibody, NF-ATc2 antibody, NFAT1 antibody, NFAT1-D antibody, Nfatp antibody, NFATP antibody, nuclear factor of activated T-cells 2 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 antibody, NFATC2 antibody, nfatc2 antibody, Nfatc2 antibody
- Background
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NFATC2 is a member of The NF-AT family of potent transcription factors that are essential for T cell activation
Alias Symbols: NFAT1, Nfatp, NF-ATc2, NFAT1-D, AI607462
Protein Interaction Partner: Foxp3, Il4, Ifng, Nfatc2ip,
Protein Size: 927 - Molecular Weight
- 100 kDa
- Gene ID
- 18019
- NCBI Accession
- NM_010899, NP_035029
- Pathways
- RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling
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