NFAT1 antibody (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2) (N-Term)

Details for Product anti-NFAT1 Antibody No. ABIN2779960, Supplier: Log in to see
Antigen
  • NFATC2
  • AI607462
  • NF-ATc2
  • NFAT1
  • NFAT1-D
  • Nfatp
  • NFATP
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
  • NFATC2
  • nfatc2
  • Nfatc2
Alternatives
anti-Human NFAT1 antibody for Immunofluorescence
Epitope
N-Term
36
15
14
6
5
5
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
150
86
79
11
7
7
6
6
5
5
1
1
1
Host
Rabbit
109
26
19
Clonality
Polyclonal
Conjugate
This NFAT1 antibody is un-conjugated
6
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
91
55
39
35
21
20
19
18
16
10
4
2
2
2
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of mouse NFATC2
Sequence MDVPEPQPDP DGGDGPGHEP GGSPQDELDF SILFDYDYLN PIEEEPIAHK
Predicted Reactivity Cow: 86%, Dog: 82%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 79%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against NFATC2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name NFATC2 (NFAT1 Antibody Abstract)
Background NFATC2 is a member of The NF-AT family of potent transcription factors that are essential for T cell activation
Alias Symbols: NFAT1, Nfatp, NF-ATc2, NFAT1-D, AI607462
Protein Interaction Partner: Foxp3, Il4, Ifng, Nfatc2ip,
Protein Size: 927
Molecular Weight 100 kDa
Gene ID 18019
NCBI Accession NM_010899, NP_035029
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 927 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (N-Term) antibody (ABIN2779960) WB Suggested Anti-NFATC2 Antibody Titration: 1.25ug/ml
ELISA Titer: ...
Product cited in: Nagamoto-Combs, Combs: "Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells)." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 28, pp. 9641-6, 2010 (PubMed).

Heer, Clarke, Rigas, Cheek, Pickard, Leung: "Phenotypic modulation of human urinary tract stroma-derived fibroblasts by transforming growth factor beta3." in: Urology, Vol. 76, Issue 2, pp. 509.e13-20, 2010 (PubMed).

Background publications Glud, Sørensen, Andrulis, Wang, Kondo, Jessen, Krenacs, Stelkovics, Wabl, Serfling, Palmetshofer, Pedersen: "A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus." in: Blood, Vol. 106, Issue 10, pp. 3546-52, 2005 (PubMed).

Did you look for something else?