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NFAT1 antibody (N-Term)

NFAT1 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779960
  • Target See all NFAT1 Antibodies
    NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
    Binding Specificity
    • 24
    • 23
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 99
    • 36
    • 23
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Horse, Pig
    Host
    • 97
    • 5
    • 1
    Rabbit
    Clonality
    • 91
    • 12
    Polyclonal
    Conjugate
    • 38
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This NFAT1 antibody is un-conjugated
    Application
    • 74
    • 28
    • 14
    • 13
    • 13
    • 12
    • 10
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MDVPEPQPDP DGGDGPGHEP GGSPQDELDF SILFDYDYLN PIEEEPIAHK
    Predicted Reactivity
    Cow: 86%, Dog: 82%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 79%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against NFATC2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of mouse NFATC2
    Top Product
    Discover our top product NFAT1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 927 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Nagamoto-Combs, Combs: "Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells)." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 28, pp. 9641-6, (2010) (PubMed).

    Heer, Clarke, Rigas, Cheek, Pickard, Leung: "Phenotypic modulation of human urinary tract stroma-derived fibroblasts by transforming growth factor beta3." in: Urology, Vol. 76, Issue 2, pp. 509.e13-20, (2010) (PubMed).

  • Target
    NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
    Alternative Name
    NFATC2 (NFAT1 Products)
    Synonyms
    NFATC2 antibody, AI607462 antibody, NF-ATc2 antibody, NFAT1 antibody, NFAT1-D antibody, Nfatp antibody, NFATP antibody, nuclear factor of activated T-cells 2 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 antibody, NFATC2 antibody, nfatc2 antibody, Nfatc2 antibody
    Background
    NFATC2 is a member of The NF-AT family of potent transcription factors that are essential for T cell activation
    Alias Symbols: NFAT1, Nfatp, NF-ATc2, NFAT1-D, AI607462
    Protein Interaction Partner: Foxp3, Il4, Ifng, Nfatc2ip,
    Protein Size: 927
    Molecular Weight
    100 kDa
    Gene ID
    18019
    NCBI Accession
    NM_010899, NP_035029
    Pathways
    RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling
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