p53 antibody (Tumor Protein P53) (C-Term)

Details for Product anti-TP53 Antibody No. ABIN2779979, Supplier: Log in to see
Antigen
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Alternatives
anti-Human p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
C-Term
174
125
91
84
74
71
70
62
59
55
50
49
48
45
42
38
32
31
28
24
22
20
17
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11
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9
9
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8
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5
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5
5
5
5
5
5
5
4
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4
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4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
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1
1
1
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1
1
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1
1
1
1
1
1
1
1
1
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1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
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1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
2387
516
423
186
126
94
85
81
35
22
19
18
16
16
15
13
6
4
4
4
4
3
3
2
2
2
1
1
Host
Rabbit
1364
1134
7
3
3
1
1
1
Clonality
Polyclonal
Conjugate
This p53 antibody is un-conjugated
81
78
65
54
46
45
31
31
26
25
25
25
25
25
25
24
24
24
22
20
19
18
14
14
14
14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Application
Western Blotting (WB)
1915
768
747
733
626
615
432
346
314
179
72
41
32
31
21
17
17
15
13
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen The immunogen is a synthetic peptide corresponding to a region of Mouse
Sequence TEEENFRKKE VLCPELPPGS AKRALPTCTS ASPPQKKKPL DGEYFTLKIR
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 100%
Characteristics This is a rabbit polyclonal antibody against TRP53. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name TRP53 (TP53 Antibody Abstract)
Background Trp53 is a protein found in elevated levels in a great variety of transformed cells
Alias Symbols: bbl, bfy, bhy, p44, p53, Tp53
Protein Interaction Partner: PRKAA1, Rnf128, Ndn, Herc2, Rchy1, Rps26, Rpl11, Cdkn2a, Bcl2l1, Daxx, Mdm2, Wwox, Mapk8, Smyd1, Ubc, Twist1, Pten, Bard1, Ep300, Sumo1, Trp73, Trp63, Strm, Nqo1, Mif, Hspa1b, Hipk2, Axin1, Zbtb7c, Topors, Gsk3b, Foxp3, Huwe1, Park7, Ccng1, NUMB, Skil, Cu
Protein Size: 390
Molecular Weight 43 kDa
Gene ID 22059
NCBI Accession NM_011640, NP_035770
UniProt P02340
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 390 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (C-Term) antibody (ABIN2779979) WB Suggested Anti-TRP53 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:...
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (C-Term) antibody (ABIN2779979) WB Suggested Anti-TRP53 Antibody
Positive Control: Lane 1:441 µg C57/B6 contro...
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (C-Term) antibody (ABIN2779979) WB Suggested Anti-TRP53
Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.12500
Background publications Rotter, Wolf, Pravtcheva, Ruddle: "Chromosomal assignment of the murine gene encoding the transformation-related protein p53." in: Molecular and cellular biology, Vol. 4, Issue 2, pp. 383-5, 1984 (PubMed).

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