RNF6 antibody (N-Term)

Catalog No. ABIN2780073

Product Details anti-RNF6 Antibody

Target: RNF6 (RING Finger Protein 6 (RNF6))

Binding Specificity: N-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MDPSRSRSGG SGEESSFQEN ERRWQQERLH REEAYYQFIN ELSDEDYRLM

Predicted Reactivity: Mouse: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against RNF6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse RNF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 667 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RNF6 antibody (ABIN2780073)

Tursun, Schlüter, Peters, Viehweger, Ostendorff, Soosairajah, Drung, Bossenz, Johnsen, Schweizer, Bernard, Bach: "The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones." in: Genes & development, Vol. 19, Issue 19, pp. 2307-19, (2005) (PubMed).

Target Details for RNF6

Target: RNF6 (RING Finger Protein 6 (RNF6))

Alternative Name: RNF6 (RNF6 Products)

Synonyms: 1200013I08Rik antibody, 5730419H05Rik antibody, AA537053 antibody, ring finger protein 6 antibody, ring finger protein (C3H2C3 type) 6 antibody, RNF6 antibody, Rnf6 antibody

Background: Rnf6 is involved in neuronal development. High Rnf6 protein levels can be detected in developing axonal projections of motor and DRG neurons during mouse embryogenesis.
Alias Symbols: AA537053, 1200013I08Rik, 5730419H05Rik
Protein Interaction Partner: Limk1,
Protein Size: 667

Molecular Weight: 73 kDa

Gene ID: 74132

NCBI Accession: NM_028774, NP_083050

UniProt: Q9DBU5

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size