LMX1A antibody (Middle Region)
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- Target See all LMX1A Antibodies
- LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LMX1A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KKLARRQQQQ QQDQQNTQRL TSAQTNGSGN AGMEGIMNPY TTLPTPQQLL
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 93%, Mouse: 100%, Rabbit: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against Lmx1a. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of mouse Lmx1a
- Top Product
- Discover our top product LMX1A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 382 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
- Alternative Name
- Lmx1a (LMX1A Products)
- Synonyms
- Lmx1.1 antibody, dr antibody, dreher antibody, sst antibody, LMX1 antibody, LMX1.1 antibody, si:ch211-260g14.3 antibody, LIM homeobox transcription factor 1 alpha antibody, LIM homeobox transcription factor 1, alpha antibody, Lmx1a antibody, LMX1A antibody, lmx1a antibody
- Background
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Lmx1a acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Lmx1a is required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.
Alias Symbols: Lmx1.1, MGC129356, MGC129357, dr, dreher, sst
Protein Interaction Partner: Phf10, Ssbp2, Ldb2, Ldb1, BMPR2,
Protein Size: 382 - Molecular Weight
- 43 kDa
- Gene ID
- 110648
- NCBI Accession
- NM_033652, NP_387501
- UniProt
- Q9JKU8
- Pathways
- Dopaminergic Neurogenesis
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