DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16) (N-Term) antibody

Details for Product No. ABIN2780219, Supplier: Log in to see
Antigen
  • fa91b12
  • zgc:55590
  • wu:fa91b12
  • dbp2
  • ddx16
  • pro2014
  • prp2
  • prp8
  • prpf2
  • DHX16
  • DKFZp459L1130
  • DBP2
  • DDX16
  • PRO2014
  • PRP8
  • PRPF2
  • Prp2
  • 2410006N22Rik
  • Ddx16
  • mKIAA0577
  • Dbp2
  • DEAH (Asp-Glu-Ala-His) box polypeptide 16
  • dhx16
  • DHX16
  • LOC100358431
  • Dhx16
Epitope
N-Term
3
2
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Goat, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
27
9
5
4
3
3
3
3
2
2
2
1
1
1
Host
Rabbit
17
11
Clonality
Polyclonal
Application
Western Blotting (WB)
24
7
7
6
4
4
2
1
1
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DHX16
Blocking Peptide Blocking peptide for this product available: ABIN975777
Sequence KYQLVLEEEE TIEFVRATQL QGDEEPSAPP TSTQAQQKES IQAVRRSLPV
Predicted Reactivity Cow: 86%, Goat: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 85%, Rabbit: 77%, Rat: 79%
Characteristics This is a rabbit polyclonal antibody against DHX16. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name DHX16 (DHX16 Antibody Abstract)
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked.
Alias Symbols: DBP2, PRP8, Prp2, DDX16, PRPF2, PRO2014
Protein Interaction Partner: NUDCD1, UBC, GPKOW, SF3B2, DHX38, DGCR14, CSNK2A1, XAB2, HELQ, PYROXD1, NAA40, LSM2, MIF4GD, GON4L, WDR44, EHD2, LSM5, LSM6, GCC2, TCEA2, MTR, GSPT1, GABPB1, APP, COIL, SNRNP27, SNRNP40, SIRT7, MEGF10, Bud13, TADA2A, SRRM2, SRRM1,
Protein Size: 1041
Molecular Weight 115 kDa
Gene ID 8449
NCBI Accession NM_003587, NP_003578
UniProt O60231
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1041 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16) (N-Term) antibody (ABIN2780219) WB Suggested Anti-DHX16 Antibody Titration: 0.125ug/ml
ELISA Titer: ...
Background publications Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

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