DDX46 antibody (C-Term)

Catalog No. ABIN2780223

Product Details anti-DDX46 Antibody

Target: DDX46 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46 (DDX46))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX46 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GERKIYLAIE SANELAVQKA KAEITRLIKE ELIRLQNSYQ PTNKGRYKVL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against DDX46. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DDX46

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1031 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DDX46

Target: DDX46 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46 (DDX46))

Alternative Name: DDX46 (DDX46 Products)

Synonyms: MMI9.2 antibody, MMI9_2 antibody, RNA HELICASE antibody, fb39a03 antibody, fj67d06 antibody, wu:fb39a03 antibody, wu:fj67d06 antibody, PRPF5 antibody, Prp5 antibody, 2200005K02Rik antibody, 8430438J23Rik antibody, AI325430 antibody, AI957095 antibody, mKIAA0801 antibody, DEAD box RNA helicase (PRH75) antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 antibody, DEAD-box helicase 46 antibody, RNA helicase-like protein antibody, PRH75 antibody, ddx46 antibody, DDX46 antibody, Ddx46 antibody, TDRD12 antibody

Background: DDX46 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX46 is a component of the 17S U2 snRNP complex, it plays an important role in pre-mRNA splicing.
Alias Symbols: Prp5, PRPF5
Protein Interaction Partner: HUWE1, UBC, RPA3, RPA2, RPA1, PRPF40A, APBB1, SRPK2, LMNA, TPM2, PNLIPRP2, SMIM20, GEMIN5, SF3A3, SRSF11, CUL3, SIRT7, SF3A2, ELAVL1, SUMO2, Sf3a1, TCEA1,
Protein Size: 1031

Molecular Weight: 113 kDa

Gene ID: 9879

NCBI Accession: NM_014829, NP_055644

UniProt: Q7L014