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SSX2 antibody (C-Term)

SSX2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780224
  • Target See all SSX2 Antibodies
    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))
    Binding Specificity
    • 15
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 40
    • 3
    • 2
    Human
    Host
    • 35
    • 5
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SSX2 antibody is un-conjugated
    Application
    • 30
    • 13
    • 13
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    HRWSSQNTHN IGRFSLSTSM GAVHGTPKTI THNRDPKGGN MPGPTDCVRE
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SSX2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human SSX2
    Top Product
    Discover our top product SSX2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 223 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Jung, Fischer, Imig, Kleber, Nuber, Reinshagen, Kamradt, Grobholz, Knuth, Renner, Wadle: "Yeast-based identification of prostate tumor antigens provides an effective vaccine platform." in: Anticancer research, Vol. 30, Issue 3, pp. 895-902, (2010) (PubMed).

  • Target
    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))
    Alternative Name
    SSX2 (SSX2 Products)
    Synonyms
    CT5.2 antibody, CT5.2A antibody, HD21 antibody, HOM-MEL-40 antibody, SSX antibody, SSX2 antibody, SSX3 antibody, SSX family member 2 antibody, protein SSX2 antibody, synovial sarcoma, X breakpoint 2 antibody, SSX2 antibody, LOC741661 antibody, Ssx2 antibody
    Background
    SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX, SSX2B, CT5.2a
    Protein Interaction Partner: KRT40, SSX2IP, RAB3IP, SYCE1, ZMIZ2, MAGEC2, AKAP9, ZBED1, TAX1BP1, BLZF1, SUZ12, EED, SMARCA5, TLE1, SMARCA2, HDAC2, HDAC1, EZH2, ATF2, RNF2,
    Protein Size: 223
    Molecular Weight
    25 kDa
    Gene ID
    6757
    NCBI Accession
    NM_003147, NP_003138
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