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PDX1 antibody (N-Term)

PDX1 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780330
  • Target See all PDX1 Antibodies
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    Binding Specificity
    • 21
    • 15
    • 14
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 119
    • 44
    • 33
    • 15
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig
    Host
    • 132
    • 8
    • 2
    Rabbit
    Clonality
    • 125
    • 17
    Polyclonal
    Conjugate
    • 61
    • 13
    • 9
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDX1 antibody is un-conjugated
    Application
    • 90
    • 67
    • 36
    • 20
    • 18
    • 14
    • 14
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MNGEEQYYAA TQLYKDPCAF QRGPAPEFSA SPPACLYMGR QPPPPPPHPF
    Predicted Reactivity
    Cow: 100%, Dog: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PDX1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PDX1
    Top Product
    Discover our top product PDX1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 283 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    Alternative Name
    PDX1 (PDX1 Products)
    Synonyms
    GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
    Background
    The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of
    Alias Symbols: IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1, GSF
    Protein Interaction Partner: UBC, MAPK14, PCIF1, Dlg4, ATF3, PBX1, XRCC5, PRKDC, XRCC6, ALK, SPOP, MAFA, NEUROD1, PDX1, IAPP, TCF3, SLC2A2, CREB1,
    Protein Size: 283
    Molecular Weight
    31 kDa
    Gene ID
    3651
    NCBI Accession
    NM_000209, NP_000200
    UniProt
    P52945
    Pathways
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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