BACH1 antibody (C-Term)

Catalog No. ABIN2780352

Product Details anti-BACH1 Antibody

Target: BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACH1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PPCARGNSEP GYARGQESQQ MSTATSEQAG PAEQCRQSGG ISDFCQQMTD

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against BACH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BACH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 736 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BACH1

Target: BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))

Alternative Name: BACH1 (BACH1 Products)

Synonyms: zgc:112205 antibody, BACH1 antibody, 6230421P05Rik antibody, AI323795 antibody, BACH-1 antibody, BTB domain and CNC homolog 1 antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 1 b antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 1 antibody, BACH1 antibody, bach1b antibody, bach1 antibody, Bach1 antibody

Background: BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.
Alias Symbols: BACH-1
Protein Interaction Partner: NFE2L2, BRCA1, SMAD3, FBXL17, NLK, UBC, MAFF, MAFB, MAFG, DDIT3, ATF2, CSNK1A1, ANAPC5, PALB2, TOPBP1, NBN, MRE11A, MLH1, BARD1, Bach1, HMMR, BRCA2, BRCC3, XPO1, NCOR1, MAFK, TP53, HDAC1, PATZ1, RBCK1, PARK2,
Protein Size: 736

Molecular Weight: 82 kDa

Gene ID: 571

NCBI Accession: NM_001186, NP_001177

UniProt: O14867