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TADA2L antibody (Middle Region)

TADA2A Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780370
  • Target See all TADA2L (TADA2A) Antibodies
    TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
    Binding Specificity
    • 10
    • 8
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 43
    • 19
    • 19
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 40
    • 3
    Rabbit
    Clonality
    • 40
    • 3
    Polyclonal
    Conjugate
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TADA2L antibody is un-conjugated
    Application
    • 36
    • 23
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LEYKSALLNE CNKQGGLRLA QARALIKIDV NKTRKIYDFL IREGYITKG
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against TADA2L. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TADA2L
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    Discover our top product TADA2A Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 443 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Thompson, Yang, Power, Hufschmid, Beveridge, Reid, Ng, Armson, Ryan: "Identification of zoonotic Giardia genotypes in marsupials in Australia." in: Experimental parasitology, Vol. 120, Issue 1, pp. 88-93, (2008) (PubMed).

  • Target
    TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
    Alternative Name
    TADA2L (TADA2A Products)
    Synonyms
    MGC81519 antibody, TADA2A antibody, TADA2L antibody, ADA2 antibody, ADA2A antibody, hADA2 antibody, AV319371 antibody, D030022J10Rik antibody, Tada2l antibody, tada2l antibody, zgc:154057 antibody, transcriptional adaptor 2A L homeolog antibody, transcriptional adaptor 2A antibody, tada2a.L antibody, TADA2A antibody, Tada2a antibody, tada2a antibody
    Background
    Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.
    Alias Symbols: ADA2, FLJ12705, KL04P, hADA2, ADA2A, TADA2L
    Protein Interaction Partner: MFAP1, MAGOH, KPNA2, FBF1, PRPF31, PPP1R16B, ZFYVE26, SF3A3, FARS2, MTX2, EIF4E2, FAM127C, KLHL38, TTC9C, ZNF564, TEKT4, LOC149950, KLC4, TTC23, GPSM3, CDCA7L, C1orf109, CCHCR1, PRKAB2, ARNT2, USP22, TADA3, HNF4A, LYN, HSP90AA1, KAT2B, MCPH1, PAXIP1, SUPT
    Protein Size: 443
    Molecular Weight
    51 kDa
    Gene ID
    6871
    NCBI Accession
    NM_001488, NP_001479
    UniProt
    O75478
    Pathways
    Chromatin Binding
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