MEIS1 antibody (N-Term)

Catalog No. ABIN2780423

Product Details anti-MEIS1 Antibody

Target: MEIS1 (Meis Homeobox 1 (MEIS1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEIS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YGDPHAARSM QPVHHLNHGP PLHSHQYPHT AHTNAMAPSM GSSVNDALKR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Meis1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 465 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEIS1

Target: MEIS1 (Meis Homeobox 1 (MEIS1))

Alternative Name: Meis1 (MEIS1 Products)

Synonyms: meis antibody, 1323/07 antibody, 1422/04 antibody, CG17117 antibody, Dm-HTH antibody, Dmel\\CG17117 antibody, HTH antibody, Hth antibody, Meis1 antibody, P53 antibody, anon-EST:Liang-2.13 antibody, clone 2.13 antibody, dtl antibody, hth1 antibody, hth2 antibody, l(3)05745 antibody, l(3)86Ca antibody, cb224 antibody, id:ibd5078 antibody, meis1.1 antibody, wu:fb38b03 antibody, wu:fc02e11 antibody, wu:fd12a02 antibody, C530044H18Rik antibody, Evi8 antibody, Meis homeobox 1 antibody, Meis homeobox 1 S homeolog antibody, homothorax antibody, Meis homeobox 1 b antibody, MEIS1 antibody, meis1.S antibody, Meis1 antibody, hth antibody, meis1b antibody, meis1 antibody

Background: Meis1 acts as a transcriptional regulator of PAX6 and a transcriptional activator of PF4 in complex with PBX1 or PBX2. It is required for hematopoiesis, megakaryocyte lineage development and vascular patterning. It may function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.
Alias Symbols: C530044H18Rik, Evi8
Protein Interaction Partner: Hoxa9, Hoxa13, Pbx1, Pdx1, Hoxd13, Hoxa11, Pbx4, Tlx1, Pknox1, Pbx3, Pbx2, Hoxa10, Hoxd12, Hoxc13, Hoxb13,
Protein Size: 465

Molecular Weight: 51 kDa

Gene ID: 17268

NCBI Accession: NM_010789, NP_034919

UniProt: Q60954

Pathways: Chromatin Binding