Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RING1 antibody (Middle Region)

RING1 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780456
  • Target See all RING1 Antibodies
    RING1 (Ring Finger Protein 1 (RING1))
    Binding Specificity
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 63
    • 19
    • 18
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse
    Host
    • 46
    • 19
    Rabbit
    Clonality
    • 47
    • 18
    Polyclonal
    Conjugate
    • 38
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RING1 antibody is un-conjugated
    Application
    • 47
    • 28
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    SDTGGPDGCG GEGGGAGGGD GPEEPALPSL EGVSEKQYTI YIAPGGGAFT
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against RING1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RING1
    Top Product
    Discover our top product RING1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 406 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RING1 (Ring Finger Protein 1 (RING1))
    Alternative Name
    RING1 (RING1 Products)
    Synonyms
    RING1A antibody, RNF1 antibody, Ring1A antibody, bap-1 antibody, bap1 antibody, ding antibody, hipi3 antibody, ring1a antibody, ring1b antibody, ring2 antibody, rnf1 antibody, rnf2-a antibody, ring1 antibody, ring1b-B antibody, rnf2-b antibody, ring finger protein 1 antibody, ring finger protein 1 S homeolog antibody, ring finger protein 1 L homeolog antibody, RING1 antibody, Ring1 antibody, ring1.S antibody, ring1.L antibody
    Background
    RING1 can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain.This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: RNF1, RING1A
    Protein Interaction Partner: CBX8, RYBP, YAF2, BMI1, UBC, SNAI1, EED, RNF2, HECW2, CSNK2A2, YY1, FBXO38, CBX7, CBX6, FHL1, TP53, NOTCH1, APP, PCGF1, PCGF5, PCGF6, PCGF3, PCGF2, CBX2, PHC3, WDR5, CBX4, PHC2, PHC1, YY2, ZFP42, SMARCAD1, PIK3R3, TOP2A, TERF2, TERF1, USP11, USP7, CENPA,
    Protein Size: 406
    Molecular Weight
    42 kDa
    Gene ID
    6015
    NCBI Accession
    NM_002931, NP_002922
    UniProt
    Q06587
You are here:
Support