SMARCA1 antibody (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 1) (N-Term)

Details for Product anti-SMARCA1 Antibody No. ABIN2780460, Supplier: Log in to see
Antigen
  • snf2l
  • MGC80667
  • SMARCA1
  • DKFZp459M1930
  • 5730494M04Rik
  • Snf2l
  • RGD1561046
  • ISWI
  • NURF140
  • SNF2L
  • SNF2L1
  • SNF2LB
  • SNF2LT
  • SWI
  • SWI2
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
  • smarca1
  • SMARCA1
  • Smarca1
Alternatives
anti-Mouse (Murine) SMARCA1 antibody for Western Blotting
Epitope
N-Term
7
4
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
33
25
24
4
4
2
2
2
1
Host
Rabbit
33
2
1
Clonality
Polyclonal
Conjugate
This SMARCA1 antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC), Western Blotting (WB)
19
13
8
5
5
3
2
2
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCA1
Sequence EQDTAAVAAT VAAADATATI VVIEDEQPGP STSQEEGAAA AATEATAATE
Predicted Reactivity Cow: 86%, Dog: 93%, Horse: 92%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 77%, Rat: 85%
Characteristics This is a rabbit polyclonal antibody against SMARCA1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SMARCA1 (SMARCA1 Antibody Abstract)
Background SMARCA1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. This gene encodes a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp686D1623, FLJ41547, ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SWI, SWI2, SNF2LT
Protein Interaction Partner: UBC, EED, TFPT, DDX21, RUVBL1, SMARCA5, SMARCC2, SMARCC1, SMARCA4, RBBP4, GRK5, SETD1A, USF1, ARID1B, PGR, BPTF, HIST1H3A, RBBP7, PARP1, BAZ1B, H3F3B,
Protein Size: 1054
Molecular Weight 122 kDa
Gene ID 6594
NCBI Accession NM_003069, NP_003060
UniProt P28370
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Pathways Chromatin Binding
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1054 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-SMARCA1 antibody (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 1) (N-Term) (ABIN2780460) WB Suggested Anti-SMARCA1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: <...
Chromatin Immunoprecipitation (ChIP) image for anti-SMARCA1 antibody (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 1) (N-Term) (ABIN2780460) Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three ...
Chromatin Immunoprecipitation (ChIP) image for anti-SMARCA1 antibody (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 1) (N-Term) (ABIN2780460) Chromatin Immunoprecipitation (ChIP) Using SMARCA1 Antibody - N-terminal region (ARP3...
Background publications Xia, Jiang, Zou, Gao, Shang, Chen, Liu, Gong: "Sp1 and CREB regulate basal transcription of the human SNF2L gene." in: Biochemical and biophysical research communications, Vol. 368, Issue 2, pp. 438-44, 2008 (PubMed).

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