SMARCA5 antibody (N-Term)

Catalog No. ABIN2780539

Product Details anti-SMARCA5 Antibody

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Binding Specificity: N-Term

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCA5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SSAAEPPPPP PPESAPSKPA ASIASGGSNS SNKGGPEGVA AQAVASAVSA

Predicted Reactivity: Horse: 93%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SMARCA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1052 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMARCA5

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Alternative Name: SMARCA5 (SMARCA5 Products)

Synonyms: fb26d12 antibody, fb49g04 antibody, chunp6878 antibody, im:7146484 antibody, wu:fb26d12 antibody, wu:fb49g04 antibody, zgc:158434 antibody, smarca5 antibody, iswi antibody, SMARCA5 antibody, hiswi antibody, snf2h antibody, hsnf2h antibody, wcrf135 antibody, MGC79455 antibody, ISWI antibody, SNF2H antibody, WCRF135 antibody, hISWI antibody, hSNF2H antibody, 4933427E24Rik antibody, D030040M08Rik antibody, D330027N15Rik antibody, MommeD4 antibody, Snf2h antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 S homeolog antibody, smarca5 antibody, smarca5.S antibody, SMARCA5 antibody, Smarca5 antibody

Background: SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ISWI, SNF2H, WCRF135, hISWI, hSNF2H
Protein Interaction Partner: SUMO2, SUMO3, HIST1H3A, UBC, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, HB-1, AT5G35210, LMNA, RSF1, BAZ1A, SMARCA5, WHSC1, SS18, SSX2, UL29, RNF168, VCP, NOTCH1, IK, HDAC2, HDAC1, CHRAC1, MBD3, PHGDH, NCSTN, POLR3A, RUVBL2, RBM14, SAP18, HNRNPR, EIF4A3, B
Protein Size: 1052

Molecular Weight: 122 kDa

Gene ID: 8467

NCBI Accession: NM_003601, NP_003592

UniProt: O60264

Pathways: Chromatin Binding