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TCEAL1 antibody (Middle Region)

TCEAL1 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780618
  • Target See all TCEAL1 Antibodies
    TCEAL1 (Transcription Elongation Factor A (SII)-Like 1 (TCEAL1))
    Binding Specificity
    • 14
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 34
    • 9
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
    Host
    • 26
    • 7
    • 1
    Rabbit
    Clonality
    • 29
    • 5
    Polyclonal
    Conjugate
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    This TCEAL1 antibody is un-conjugated
    Application
    • 33
    • 21
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RPQFRGDIHG RNLSNEEMIQ AADELEEMKR VRNKLMIMHW KAKRSRPYPI
    Predicted Reactivity
    Cow: 85%, Dog: 85%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TCEAL1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TCEAL1
    Top Product
    Discover our top product TCEAL1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 159 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Klos, Wyszomierski, Sun, Tan, Zhou, Li, Yang, Yin, Hittelman, Yu: "ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells." in: Cancer research, Vol. 66, Issue 4, pp. 2028-37, (2006) (PubMed).

  • Target
    TCEAL1 (Transcription Elongation Factor A (SII)-Like 1 (TCEAL1))
    Alternative Name
    TCEAL1 (TCEAL1 Products)
    Synonyms
    SIIR antibody, p21 antibody, pp21 antibody, 0610011M09Rik antibody, BC011290 antibody, P21 antibody, transcription elongation factor A like 1 antibody, transcription elongation factor A (SII)-like 1 antibody, TCEAL1 antibody, Tceal1 antibody
    Background
    TCEAL1 is a member of the transcription elongation factor A (SII)-like (TCEAL) protein family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. TCEAL1 is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.
    Alias Symbols: SIIR, p21, pp21
    Protein Interaction Partner: MAPK14, DYRK1B, UBC, HOXB6, USP11, TCEAL2, TCEAL4, FEM1C, PPP2R2D, KDM3A, FEM1A, TIPIN, PDCD5, GMPS, CUL2, USP7, TCEB1, RFC1, HSPA4L, SSR3, PPP2R2A,
    Protein Size: 159
    Molecular Weight
    19 kDa
    Gene ID
    9338
    NCBI Accession
    NM_004780, NP_004771
    UniProt
    Q15170
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