MYB antibody (N-Term)

Catalog No. ABIN2780679

Product Details anti-MYB Antibody

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: YDGLLPKSGK RHLGKTRWTR EEDEKLKKLV EQNGTDDWKV IANYLPNRTD

Specificity: Based on the sequence of the immunizing peptide, this antibody is 100 % homologous to all 12 isoforms of hMYB.

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against MYB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 323 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: MYB (MYB Products)

Synonyms: Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody

Background: MYB may be a transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. It plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Alias Symbols: Cmyb, c-myb, c-myb_CDS, efg
Protein Interaction Partner: UBC, ERC2, UPF2, PPM1K, MYOZ2, SUMO1, SUMO2, CCND3, EP300, RBX1, FBXW5, PIAS1, CUL4A, UBE2I, DDB1, TRAF6, STAT5A, GATA3, KAT5, Fbxw7, CREBBP, LEF1, RPL4, KAT2B, CHD3, SIN3A, TRIM28, NCOR1, SKI, HIPK2, NLK, SP100, HLF, PARP1, ASH2L, RBBP5, KMT2A, MEN1, WDR
Protein Size: 323

Molecular Weight: 38 kDa

Gene ID: 4602

NCBI Accession: NM_001130172

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process