Tumor Protein p73 antibody (Middle Region)

Catalog No. ABIN2780685

Product Details anti-Tumor Protein p73 Antibody

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tumor Protein p73 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VHFRVRHTIT IPNRGGPGGG PDEWADFGFD LPDCKARKQP IKEEFTEAEI

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 91%, Human: 100%, Mouse: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against TP73. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TP73

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 636 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: TP73 (TP73 Products)

Synonyms: P73 antibody, Trp73 antibody, TP73 antibody, tp73 antibody, Tp73 antibody, p73 antibody, TAp73 antibody, zp73theta antibody, tumor protein p73 antibody, transformation related protein 73 antibody, TP73 antibody, Tp73 antibody, tp73 antibody, Trp73 antibody

Background: TP73 belongs to the p53 family. It participates in the apoptotic response to DNA damage. When overproduced, it activates transcription from p53-responsive promoters and induces apoptosis. TP53 may be a tumor suppressor protein.
Alias Symbols: P73
Protein Interaction Partner: FUS, YAP1, WWOX, UBC, TRIM32, SOX2, PFDN5, MYC, EP300, CDK2, CCNE1, CCNB1, CCNA2, CCND1, XPO1, PIN1, AURKA, PRKACA, MAD2L1, HSPA9, CDC20, TP53BP1, RBX1, DDB1, RCHY1, KAT2B, NEDD8, MDM2, IKBKB, DAXX, CHUK, BUB1B, BRCA1, TNK2, AMPH, CREBBP, KAT5, CEP131, MD
Protein Size: 636

Molecular Weight: 69 kDa

Gene ID: 7161

NCBI Accession: NM_005427, NP_005418

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus