NEUROD2 antibody (C-Term)

Catalog No. ABIN2780746

Product Details anti-NEUROD2 Antibody

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEUROD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGSRPTGHGL VFGSSAVRGG VHSENLLSYD MHLHHDRGPM YEELNAFFHN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NEUROD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NEUROD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 382 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEUROD2

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Alternative Name: NEUROD2 (NEUROD2 Products)

Synonyms: NEUROD2 antibody, ndrf antibody, MGC145932 antibody, Ndrf antibody, bHLHa1 antibody, ndr2 antibody, wu:fj49a11 antibody, zNdr2 antibody, NDRF antibody, neuronal differentiation 2 antibody, neurogenic differentiation 2 antibody, NEUROD2 antibody, neurod2 antibody, Neurod2 antibody

Background: NEUROD2 is a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of NEUROD2 can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
Alias Symbols: NDRF, bHLHa1
Protein Interaction Partner: TK1, PKN1,
Protein Size: 382

Molecular Weight: 41 kDa

Gene ID: 4761

NCBI Accession: NM_006160, NP_006151

UniProt: Q15784