KAT5 antibody (N-Term)

Catalog No. ABIN2780772

Product Details anti-KAT5 Antibody

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Goat, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: EGCRLPVLRR NQDNEDEWPL AEILSVKDIS GRKLFYVHYI DFNKRLDEWV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HTATIP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTATIP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 546 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Alternative Name: HTATIP (KAT5 Products)

Background: HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: TIP, ESA1, PLIP, TIP60, cPLA2, HTATIP, HTATIP1
Protein Interaction Partner: SOX5, SIRT1, MTUS2, NINL, IKZF3, TMCC2, ESR1, PHC2, TRIM23, APBB1, STX11, ZBTB14, TUFT1, TRIM27, ODC1, TRIM37, MEOX2, MDFI, HDAC1, GOLGA2, ZBTB8A, KRTAP10-3, KRTAP10-9, PIH1D3, ZNF513, KRT40, SSX2IP, LONRF1, LZTS2, HMBOX1, CCDC136, GMCL1P1, GMCL1, ZBTB7B,
Protein Size: 546

Molecular Weight: 62 kDa

Gene ID: 10524

NCBI Accession: NM_182710, NP_874369

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway