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ZNF175 antibody (N-Term)

ZNF175 Reactivity: Human, Cow, Horse, Mouse, Pig, Rat, Dog, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780831
  • Target See all ZNF175 Antibodies
    ZNF175 (Zinc Finger Protein 175 (ZNF175))
    Binding Specificity
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Cow, Horse, Mouse, Pig, Rat, Dog, Rabbit
    Host
    • 14
    • 2
    Rabbit
    Clonality
    • 14
    • 2
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    This ZNF175 antibody is un-conjugated
    Application
    • 11
    • 8
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    FSREEWQQLD PAQRCLYRDV MLELYSHLFA VGYHIPNPEV IFRMLKEKEP
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against ZNF175. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF175
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    Discover our top product ZNF175 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 711 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Carlson, Limoges, Pohlman, Poluektova, Langford, Masliah, Ikezu, Gendelman: "OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis." in: Journal of neuroimmunology, Vol. 150, Issue 1-2, pp. 186-98, (2004) (PubMed).

  • Target
    ZNF175 (Zinc Finger Protein 175 (ZNF175))
    Alternative Name
    ZNF175 (ZNF175 Products)
    Synonyms
    ZNF175 antibody, OTK18 antibody, zinc finger protein 175 antibody, ZNF175 antibody
    Background
    ZNF175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. As a transcriptional suppressor, this protein plays a role in macrophage control of viral replication during advanced HIV-1 infection.
    Alias Symbols: OTK18
    Protein Interaction Partner: KRTAP10-7, ZNF250, ZNF264, PSTPIP1, ALAS1, LPXN, UBC, LZTR1, CDC42,
    Protein Size: 711
    Molecular Weight
    81 kDa
    Gene ID
    7728
    NCBI Accession
    NM_007147, NP_009078
    UniProt
    Q9Y473
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