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MafF antibody (N-Term)

MAFF Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780877
  • Target See all MafF (MAFF) Antibodies
    MafF (MAFF) (Transcription Factor MafF (MAFF))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 21
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit
    Host
    • 20
    • 1
    Rabbit
    Clonality
    • 20
    • 1
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MafF antibody is un-conjugated
    Application
    • 10
    • 6
    • 4
    • 4
    • 1
    Western Blotting (WB)
    Sequence
    SVRELNRHLR GLSAEEVTRL KQRRRTLKNR GYAASCRVKR VCQKEELQKQ
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against MAFF. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human MAFF
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  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 164 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MafF (MAFF) (Transcription Factor MafF (MAFF))
    Alternative Name
    MAFF (MAFF Products)
    Synonyms
    zgc:63868 antibody, MAFF antibody, U-MAF antibody, hMafF antibody, MAF bZIP transcription factor F antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F S homeolog antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) antibody, Maff antibody, maff antibody, MAFF antibody, maff.S antibody
    Background
    MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: U-MAF, hMafF
    Protein Interaction Partner: NFE2L2, PARP1, BACH2, BATF3, MAFF, NFE2L3, NFIL3, NFE2L1, MAFG, FOS, DDIT3, BACH1, ATF3, BATF2, MAFIP, OVOL1, SUMO2, GTF2A1L, HDAC5, PPARG, NR3C1, NFE2, NRF1, PSAP, PRRX1, HOXD12,
    Protein Size: 164
    Molecular Weight
    18 kDa
    Gene ID
    23764
    NCBI Accession
    NM_152878, NP_690617
    UniProt
    Q9ULX9
    Pathways
    Myometrial Relaxation and Contraction
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