BRD7 antibody (C-Term)

Catalog No. ABIN2780896

Product Details anti-BRD7 Antibody

Target: BRD7 (Bromodomain Containing 7 (BRD7))

Binding Specificity: C-Term

Reactivity: Human, Rat, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KELAQQVTPG DIVSTYGVRK AMGISIPSPV MENNFVDLTE DTEEPKKTDV

Predicted Reactivity: Dog: 86%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against BRD7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 651 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BRD7 antibody (ABIN2780896)

Zhou, Tan, Hershenson: "Yersinia YopJ inhibits pro-inflammatory molecule expression in human bronchial epithelial cells." in: Respiratory physiology & neurobiology, Vol. 140, Issue 1, pp. 89-97, (2004) (PubMed).

Target Details for BRD7

Target: BRD7 (Bromodomain Containing 7 (BRD7))

Alternative Name: BRD7 (BRD7 Products)

Synonyms: zgc:66347 antibody, wu:fc95f02 antibody, MGC79478 antibody, BRD7 antibody, BP75 antibody, CELTIX1 antibody, NAG4 antibody, Ptpn13ip antibody, bromodomain containing 7 L homeolog antibody, bromodomain containing 7 antibody, brd7.L antibody, brd7 antibody, BRD7 antibody, Brd7 antibody

Background: BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'.
Alias Symbols: BP75, CELTIX1, NAG4
Protein Interaction Partner: UBC, Dvl1, HIST2H3C, BRD2, NEFL, BARD1, LRIF1, HAP1, TFAP4, TRIM24, SUMO2, SMARCE1, SMARCD1, SMARCC2, Bcl7b, CHD7, ARID2, RBFOX2, BCL7C, SMARCC1, SMARCA4, PCBD1, POU2F1, MYC, BRCA1, BHLHE40, HIST2H4A, HIST2H3A, BTBD2, RIF1, HNRNPUL1, HIST1H2AL, AGR2, PSMD
Protein Size: 651

Molecular Weight: 74 kDa

Gene ID: 29117

NCBI Accession: NM_013263, NP_037395

UniProt: Q9NPI1