UHRF1 antibody (N-Term)

Catalog No. ABIN2780898

Product Details anti-UHRF1 Antibody

Target: UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGVFAVPPLS ADTMWIQVRT MDGRQTHTVD SLSRLTKVEE LRRKIQELFH

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rat: 86%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against UHRF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UHRF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 806 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UHRF1

Target: UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))

Alternative Name: UHRF1 (UHRF1 Products)

Synonyms: ICBP90 antibody, Np95 antibody, RNF106 antibody, hNP95 antibody, hUHRF1 antibody, AL022808 antibody, NP95 antibody, fb97f09 antibody, wu:fb97f09 antibody, zgc:63539 antibody, UHRF1 antibody, ubiquitin like with PHD and ring finger domains 1 antibody, ubiquitin-like, containing PHD and RING finger domains, 1 antibody, ubiquitin-like with PHD and ring finger domains 1 antibody, UHRF1 antibody, Uhrf1 antibody, uhrf1 antibody

Background: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2
Alias Symbols: FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95
Protein Interaction Partner: UBC, H3F3B, H3F3A, HIST2H3D, HIST2H3A, HIST2H3C, UHRF1, HIST1H3F, HIST1H3B, HIST1H3E, HIST1H3C, HIST1H3D, HIST1H3A, HIST3H3, DNMT1, PARP1, PARP2, RNF2, USP7, KAT5, MPG, BTRC, CUL1, ZPR1, RB1, PRKACA, PML, SUV39H1, EZH2, SUZ12, UHRF2, USP11, HDAC1, ELAVL1,
Protein Size: 806

Molecular Weight: 91 kDa

Gene ID: 29128

NCBI Accession: NM_013282, NP_037414

UniProt: Q2HIX7