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SART3 antibody (N-Term)

SART3 Reactivity: Human, Rat, Guinea Pig, Dog, Horse, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780944
  • Target See all SART3 Antibodies
    SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
    Binding Specificity
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 29
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Guinea Pig, Dog, Horse, Pig
    Host
    • 26
    • 2
    • 1
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SART3 antibody is un-conjugated
    Application
    • 17
    • 9
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    TSASEPEAES KAGPKADGEE DEVKAARTRR KVLSRAVAAA TYKTMGPAWD
    Predicted Reactivity
    Dog: 77%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against SART3. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SART3
    Top Product
    Discover our top product SART3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 364 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kaji, Mizukoshi, Yamashita, Arai, Sunagozaka, Fushimi, Nakagawa, Yamada, Terashima, Kitahara, Kaneko: "Cellular Immune Responses for Squamous Cell Carcinoma Antigen Recognized by T Cells 3 in Patients with Hepatocellular Carcinoma." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170291, (2017) (PubMed).

  • Target
    SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
    Alternative Name
    SART3 (SART3 Products)
    Synonyms
    SART3 antibody, DKFZp469J2418 antibody, si:ch211-191d15.4 antibody, wu:fc51h03 antibody, DSAP1 antibody, P100 antibody, RP11-13G14 antibody, TIP110 antibody, p110 antibody, p110(nrb) antibody, AU045857 antibody, mKIAA0156 antibody, squamous cell carcinoma antigen recognized by T-cells 3 antibody, squamous cell carcinoma antigen recognized by T-cells 3 L homeolog antibody, squamous cell carcinoma antigen recognized by T cells 3 antibody, SART3 antibody, sart3 antibody, sart3.L antibody, Sart3 antibody
    Background
    SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.
    Alias Symbols: P100, p110, DSAP1, TIP110, p110(nrb), RP11-13G14
    Protein Interaction Partner: APBB1, PRPF3, Usp15, AMOT, SF3B1, NUP160, LRPPRC, THRAP3, BCLAF1, VARS, UBC, SUMO2, RAB1A, NEFM, IARS, HIF1A, DSG2, DHX9, MEPCE, HIST2H2BE, HIST2H2AC, RNF2, BMI1, RUFY1, NRBP1, PSME4, AKAP2, COPS5, NUP50, POP7, ARHGEF10, PSMB3, PSMA5, PSMA3, POLR2H, CAST,
    Protein Size: 364
    Molecular Weight
    40 kDa
    Gene ID
    9733
    NCBI Accession
    NM_014706
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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