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PRRX2 antibody (N-Term)

PRRX2 Reactivity: Mouse, Human, Rat, Horse, Pig, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781006
  • Target See all PRRX2 Antibodies
    PRRX2 (Paired Related Homeobox 2 (PRRX2))
    Binding Specificity
    • 14
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Mouse, Human, Rat, Horse, Pig, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 31
    • 5
    Rabbit
    Clonality
    • 34
    • 2
    Polyclonal
    Conjugate
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRRX2 antibody is un-conjugated
    Application
    • 29
    • 17
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RKNFSVSHLL DLEEVAAAGR LAARPGARAE AREGAAREPS GGSSGSEAAP
    Predicted Reactivity
    Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 79%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against PRRX2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PRRX2
    Top Product
    Discover our top product PRRX2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 253 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tokutomi, Araki, Kataoka, Yamamoto, Kim-Mitsuyama: "Oxidation of Prx2 and phosphorylation of GRP58 by angiotensin II in human coronary smooth muscle cells identified by 2D-DIGE analysis." in: Biochemical and biophysical research communications, Vol. 364, Issue 4, pp. 822-30, (2007) (PubMed).

  • Target
    PRRX2 (Paired Related Homeobox 2 (PRRX2))
    Alternative Name
    PRRX2 (PRRX2 Products)
    Synonyms
    Prx2 antibody, PRRX2 antibody, PMX2 antibody, PRX2 antibody, S8 antibody, (S8) antibody, PRX-2 antibody, paired related homeobox 2 antibody, Prrx2 antibody, PRRX2 antibody
    Background
    PRRX2 is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
    Alias Symbols: MGC19843, PMX2, PRX2
    Protein Interaction Partner: SOX10,
    Protein Size: 253
    Molecular Weight
    27 kDa
    Gene ID
    51450
    NCBI Accession
    NM_016307, NP_057391
    UniProt
    Q99811
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