KDM3B antibody (C-Term)

Catalog No. ABIN2781017

Product Details anti-KDM3B Antibody

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM3B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VHNLYSCIKV AEDFVSPEHV KHCFRLTQEF RHLSNTHTNH EDKLQVKNII

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against JMJD1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1761 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KDM3B

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Alternative Name: JMJD1B (KDM3B Products)

Synonyms: KDM3B antibody, JMJD1B antibody, 5830462I21Rik antibody, JHDM2B antibody, Jmjd1b antibody, mKIAA1082 antibody, 5qNCA antibody, C5orf7 antibody, NET22 antibody, lysine demethylase 3B antibody, lysine (K)-specific demethylase 3B antibody, lysine-specific demethylase 3B antibody, KDM3B lysine (K)-specific demethylase 3B antibody, KDM3B antibody, LOC100540242 antibody, kdm3b antibody, Kdm3b antibody

Background: JMJD1B contains a highly-conserved C-terminus containing a zinc finger with the unique spacing Cys-X2-Cys-X7-His-X2-Cys-X2-Cys-X4-Cys-X2-Cys and a jmjC domain. It plays an important role in histone demethylation and may be a candidate for tumor suppressors.
Alias Symbols: 5qNCA, NET22, C5orf7, JMJD1B
Protein Interaction Partner: UBC, WWOX, SPAG8, NCS1, SRP68, ZNF512B, VCP, HIST3H3, CREBBP, ELAVL1, SUMO2, ESRRA, USP18,
Protein Size: 1761

Molecular Weight: 192 kDa

Gene ID: 51780

NCBI Accession: NM_016604, NP_057688

UniProt: Q7LBC6

Pathways: Warburg Effect