PHF21A antibody (N-Term)

Catalog No. ABIN2781018

Product Details anti-PHF21A Antibody

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF21A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MELQTLQEAL KVEIQVHQKL VAQMKQDPQN ADLKKQLHEL QAKITALSEK

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PHF21A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHF21A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 634 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PHF21A antibody (ABIN2781018)

Hailesellasse Sene, Porter, Palidwor, Perez-Iratxeta, Muro, Campbell, Rudnicki, Andrade-Navarro: "Gene function in early mouse embryonic stem cell differentiation." in: BMC genomics, Vol. 8, pp. 85, (2007) (PubMed).

Target Details for PHF21A

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Alternative Name: PHF21A (PHF21A Products)

Synonyms: PHF21A antibody, im:7138823 antibody, si:dkey-23n7.9 antibody, BHC80 antibody, RGD1560612 antibody, 80kDa antibody, Bhc antibody, Bhc80 antibody, D030065N23Rik antibody, PFTF1 antibody, fj98d03 antibody, phf21a antibody, wu:fj98d03 antibody, PHD finger protein 21A antibody, PHD finger protein 21Aa antibody, PHD finger protein 21Ab antibody, PHF21A antibody, phf21aa antibody, pf21a antibody, phf21a antibody, LOC100549929 antibody, Phf21a antibody, phf21ab antibody

Background: PHF21A (BHC80) is a component of a BRAF35/histone deacetylase complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS). BHC80 is a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC, see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).[supplied by OMIM].
Alias Symbols: BHC80, BM-006, KIAA1696
Protein Interaction Partner: KRT40, BANP, NUP62, ZYX, TRAF1, FHL3, HDAC2, HDAC1, HIST3H3, HMG20B, ELAVL1, SUMO2, HIST2H3C, ESCO2, KDM1A, TAF10, RCOR1, LPXN, GTF2I,
Protein Size: 634

Molecular Weight: 70 kDa

Gene ID: 51317

NCBI Accession: NM_016621, NP_057705

Pathways: Feeding Behaviour