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RRN3 antibody (Middle Region)

RRN3 Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781066
  • Target See all RRN3 Antibodies
    RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))
    Binding Specificity
    • 9
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 38
    • 12
    • 12
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Guinea Pig
    Host
    • 34
    • 4
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRN3 antibody is un-conjugated
    Application
    • 31
    • 20
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DPIYQVWEDM SAEELQEFKK PMKKDIVEDE DDDFLKGEVP QNDTVIGITP
    Predicted Reactivity
    Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against RRN3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RRN3
    Top Product
    Discover our top product RRN3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 651 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Amit, Sela, Keren, Melamed, Muler, Shomron, Izraeli, Ast: "Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene." in: BMC molecular biology, Vol. 8, pp. 109, (2008) (PubMed).

  • Target
    RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))
    Alternative Name
    RRN3 (RRN3 Products)
    Synonyms
    RRN3 antibody, DKFZp459B073 antibody, CG16938 antibody, CG3278 antibody, CG5951 antibody, Dmel\\CG3278 antibody, TIF-1A antibody, TIF-IA antibody, Tif-1A antibody, TifIA antibody, dTIF-IA antibody, dyak_GLEANR_13182 antibody, DyakGE12956 antibody, GE12956 antibody, Tif-IA antibody, A-270G1.2 antibody, TIFIA antibody, RGD1305001 antibody, AL023001 antibody, E130302O19Rik antibody, R75565 antibody, Tif1a antibody, RRN3 homolog, RNA polymerase I transcription factor antibody, RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) antibody, CG3278 gene product from transcript CG3278-RA antibody, GE12956 gene product from transcript GE12956-RA antibody, RRN3 homolog, RNA polymerase I transcription factor L homeolog antibody, RRN3 RNA polymerase I transcription factor homolog (yeast) antibody, RRN3 antibody, rrn3 antibody, Tif-IA antibody, Dyak\Tif-IA antibody, rrn3.L antibody, Rrn3 antibody
    Background
    RRN3 is RNA polymerase I-specific transcription initiation factor. Phosphorylation of RRN3 by MAPK cascades links cell signaling with the control of gene expression, namely results in rRNA synthesis in turn cell growth.
    Alias Symbols: DKFZp566E104, MGC104238, TIFIA, A-270G1.2
    Protein Interaction Partner: UBC, ACTA1, Polr1e, POLR1B, EIF3L, NMI, RBM15, UBD, Trim28, ELAVL1, TAF1D, POLR1A, MYO1C, TAF1C, TAF1B, TAF1A, UBTF, TBP, PPP2R2A, CDK2, CCNE1, RIBIN, ACTB,
    Protein Size: 651
    Molecular Weight
    74 kDa
    Gene ID
    54700
    NCBI Accession
    NM_018427, NP_060897
    UniProt
    Q9NYV6
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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