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DEAF1 antibody (C-Term)

DEAF1 Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781133
  • Target See all DEAF1 Antibodies
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    Binding Specificity
    • 15
    • 10
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 52
    • 25
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Dog, Pig, Horse
    Host
    • 62
    • 6
    Rabbit
    Clonality
    • 63
    • 5
    Polyclonal
    Conjugate
    • 27
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DEAF1 antibody is un-conjugated
    Application
    • 56
    • 35
    • 13
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    TGCHKVNYCS TFCQRKDWKD HQHICGQSAA VTVQADEVHV AESVMEKVTV
    Predicted Reactivity
    Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against DEAF1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human DEAF1
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    Discover our top product DEAF1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 565 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    Alternative Name
    DEAF1 (DEAF1 Products)
    Synonyms
    AU042387 antibody, C230009B13Rik antibody, NUDR antibody, SPN antibody, ZMYND5 antibody, MYND5 antibody, spn antibody, DEAF1 antibody, nudr antibody, zmynd5 antibody, CG8567 antibody, DEAF-1 antibody, Deaf-1 antibody, Dmel\\CG8567 antibody, deaf1 antibody, l(3)76BDv antibody, deformed epidermal autoregulatory factor 1 (Drosophila) antibody, DEAF1, transcription factor antibody, DEAF1 transcription factor antibody, deformed epidermal autoregulatory factor 1 homolog antibody, Deformed epidermal autoregulatory factor-1 antibody, Deaf1 antibody, DEAF1 antibody, LOC509260 antibody, deaf1 antibody, deaf-1 antibody
    Background
    DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
    Alias Symbols: SPN, NUDR, ZMYND5
    Protein Interaction Partner: IRF7, IRF3, CREB1, PELI1, PELI2, HRSP12, GSK3B, GSK3A, CDKN2A, PPP1CC, PPP1CA, CDC37, AIMP2, TK1, RAD23B, PIN1, HRAS, FHL1, CDKN1A, ASCC2, INTS1, LMO4, DEAF1,
    Protein Size: 565
    Molecular Weight
    59 kDa
    Gene ID
    10522
    NCBI Accession
    NM_021008, NP_066288
    UniProt
    O75398
    Pathways
    Tube Formation
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