FOXA2 antibody (C-Term)

Catalog No. ABIN2781159

Product Details anti-FOXA2 Antibody

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QVMHYPGYGS PMPGSLAMGP VTNKTGLDAS PLAADTSYYQ GVYSRPIMNS

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FOXA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 457 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Alternative Name: FOXA2 (FOXA2 Products)

Synonyms: hnf3b antibody, tcf3b antibody, hnf3beta antibody, hnf3-beta antibody, FOXA2 antibody, HNF3B antibody, TCF3B antibody, HNF-3B antibody, ax antibody, axl antibody, fkd1 antibody, ik:tdsubc_2g8 antibody, tdsubc_2g8 antibody, wu:fe05g04 antibody, xx:tdsubc_2g8 antibody, FoxA2-A antibody, FoxA2a antibody, xFD-3 antibody, xbeta-1 antibody, HNF-3b antibody, HNF3-beta antibody, HNF3beta antibody, Hnf-3b antibody, Hnf3b antibody, Tcf-3b antibody, Tcf3b antibody, HNF-3BETA antibody, forkhead box A2 antibody, forkhead box A2 L homeolog antibody, foxa2 antibody, FOXA2 antibody, foxa2.L antibody, Foxa2 antibody

Background: FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: HNF3B, TCF3B
Protein Interaction Partner: PPARGC1B, GSC, EN2, OTX2, ONECUT1, NCOA1, TLE1, MIP, HOXA5, LHX1,
Protein Size: 457

Molecular Weight: 48 kDa

Gene ID: 3170

NCBI Accession: NM_021784, NP_068556

UniProt: Q9Y261

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process