HOXB4 antibody (N-Term)

Catalog No. ABIN2781201

Product Details anti-HOXB4 Antibody

Target: HOXB4 (Homeobox B4 (HOXB4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FLINSNYVDP KFPPCEEYSQ SDYLPSDHSP GYYAGGQRRE SSFQPEAGFG

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXB4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 251 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXB4

Target: HOXB4 (Homeobox B4 (HOXB4))

Alternative Name: HOXB4 (HOXB4 Products)

Background: HOXB4 is a nuclear protein with a homeobox DNA-binding domain. The protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
Alias Symbols: HOX-2.6, HOX2, HOX2F
Protein Interaction Partner: DDB1, RBX1, CUL4A, CREBBP, EP300, MEIS1,
Protein Size: 251

Molecular Weight: 28 kDa

Gene ID: 3214

NCBI Accession: NM_024015, NP_076920

UniProt: P17483