HECTD2 antibody (C-Term)

Catalog No. ABIN2781287

Product Details anti-HECTD2 Antibody

Target: HECTD2 (HECT Domain Containing 2 (HECTD2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Rabbit, Rat, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HECTD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TDLTIKYFWD VVLGFPLDLQ KKLLHFTTGS DRVPVGGMAD LNFKISKNET

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HECTD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HECTD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 776 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HECTD2 antibody (ABIN2781287)

Sun, Wang, He, Sweeney, Liu, Brown, Balk, Lee, Kantoff: "MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A." in: Oncogene, Vol. 33, Issue 21, pp. 2790-800, (2014) (PubMed).

Target Details for HECTD2

Target: HECTD2 (HECT Domain Containing 2 (HECTD2))

Alternative Name: HECTD2 (HECTD2 Products)

Synonyms: hmm77879 antibody, HECTD2 antibody, DKFZp459J1430 antibody, 4921524L07 antibody, A630025O09Rik antibody, AW212605 antibody, HECT domain E3 ubiquitin protein ligase 2 antibody, HECT domain containing E3 ubiquitin protein ligase 2 antibody, Probable E3 ubiquitin-protein ligase HECTD2 antibody, HECT domain containing 2 antibody, HECTD2 antibody, hectd2 antibody, hecd2 antibody, Hectd2 antibody

Background: HECTD2 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Alias Symbols: FLJ16050
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 776

Molecular Weight: 88 kDa

Gene ID: 143279

NCBI Accession: NM_182765, NP_877497

UniProt: Q5RD78