TRIM54 antibody (N-Term)

Catalog No. ABIN2781289

Product Details anti-TRIM54 Antibody

Target: TRIM54 (Tripartite Motif Containing 54 (TRIM54))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM54 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NFTVGFKPLL GDAHSMDNLE KQLICPICLE MFSKPVVILP CQHNLCRKCA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIM54. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM54

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 400 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM54

Target: TRIM54 (Tripartite Motif Containing 54 (TRIM54))

Alternative Name: TRIM54 (TRIM54 Products)

Synonyms: MGC80214 antibody, si:dkey-221h15.2 antibody, DKFZp468L1522 antibody, MURF antibody, MURF-3 antibody, RNF30 antibody, muRF3 antibody, 4930486E09Rik antibody, 4930566I02Rik antibody, MuRF3 antibody, Rnf30 antibody, tripartite motif containing 54 antibody, tripartite motif containing 54 S homeolog antibody, tripartite motif-containing 54 antibody, TRIM54 antibody, trim54.S antibody, trim54 antibody, Trim54 antibody

Background: TRIM54 contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: MURF, MURF-3, RNF30, muRF3
Protein Interaction Partner: KRT6A, CCDC146, TSHZ3, TRIM54, EXOSC5, LIN37, NGLY1, RCOR3, TBC1D22B, RBM41, CCDC87, WDYHV1, C1orf109, ING3, DCUN1D1, MBD3, SPG21, VPS28, CHCHD2, RABGEF1, CYTH4, INPP5J, OSTF1, CCDC28A, ARFIP2, KDM1A, SNF8, MID2, FARS2, DNAL4, THOC1, EPM2AIP1, ELMO1, UTP1
Protein Size: 400

Molecular Weight: 45 kDa

Gene ID: 57159

NCBI Accession: NM_032546, NP_115935

UniProt: Q9BYV2