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ABCA1 antibody (Middle Region)

ABCA1 Reactivity: Mouse, Human, Rat, Guinea Pig, Dog, Cow, Horse, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781512
  • Target See all ABCA1 Antibodies
    ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
    Binding Specificity
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Mouse, Human, Rat, Guinea Pig, Dog, Cow, Horse, Pig, Rabbit
    Host
    • 38
    • 14
    • 6
    • 2
    Rabbit
    Clonality
    • 40
    • 20
    Polyclonal
    Conjugate
    • 36
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCA1 antibody is un-conjugated
    Application
    • 30
    • 13
    • 13
    • 12
    • 10
    • 10
    • 9
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    NRRAFGDKQS CLHPFTEDDA VDPNDSDIDP ESRETDLLSG MDGKGSYQLK
    Predicted Reactivity
    Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against Abca1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide corresponding to a region of Mouse
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    Discover our top product ABCA1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 2261 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

  • Target
    ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
    Alternative Name
    Abca1 (ABCA1 Products)
    Synonyms
    ABC-1 antibody, ABC1 antibody, CERP antibody, HDLDT1 antibody, TGD antibody, ABCA1 antibody, Abc1 antibody, ATP-binding cassette A1 antibody, Arabidopsis thaliana ATP-binding cassette A1 antibody, AtABCA1 antibody, im:7136239 antibody, sb:cb407 antibody, wu:fa07e06 antibody, zgc:171581 antibody, ATP binding cassette subfamily A member 1 antibody, ATP-binding cassette, sub-family A (ABC1), member 1 antibody, ATP-binding cassette A1 antibody, ATP-binding cassette, sub-family A (ABC1), member 1B antibody, ABCA1 antibody, Abca1 antibody, abca1 antibody, abca1b antibody
    Background
    Abca1 is a cAMP-dependent and sulfonylurea-sensitive anion transporter. Abca1 is a key gatekeeper influencing intracellular cholesterol transport.
    Alias Symbols: Abc1
    Protein Interaction Partner: Sptlc1, Ubc,
    Protein Size: 2261
    Molecular Weight
    254 kDa
    Gene ID
    11303
    NCBI Accession
    NM_013454, NP_038482
    UniProt
    B1AWZ8
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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