SLC22A12 antibody (N-Term)

Catalog No. ABIN2781716

Product Details anti-SLC22A12 Antibody

Target: SLC22A12 (Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SMLENFSAAV PSHRCWAPLL DNSTAQASIL GSLSPEALLA ISIPPGPNQR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC22A12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 553 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC22A12

Target: SLC22A12 (Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12))

Alternative Name: SLC22A12 (SLC22A12 Products)

Synonyms: AI987855 antibody, OAT4L antibody, Rst antibody, Slc22al2 antibody, URAT1 antibody, RST antibody, solute carrier family 22 (organic anion/cation transporter), member 12 antibody, solute carrier family 22 member 12 antibody, Slc22a12 antibody, SLC22A12 antibody

Background: SLC22A12 is required for efficient urate re-absorption in the kidney. SLC22A12 regulates blood urate levels. SLC22A12 mediates saturable urate uptake by facilitating the exchange of urate against organic anions.The protein encoded by this gene is a urate transporter and urate-anion exchanger which regulates the level of urate in the blood. This protein is an integral membrane protein primarily found in kidney. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: OAT4L, RST, URAT1
Protein Interaction Partner: PDZK1,
Protein Size: 553

Molecular Weight: 59 kDa

Gene ID: 116085

NCBI Accession: NM_144585, NP_653186

UniProt: Q96S37