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EPOR antibody (N-Term)

EPOR Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Goat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781766
  • Target See all EPOR Antibodies
    EPOR (Erythropoietin Receptor (EPOR))
    Binding Specificity
    • 16
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 119
    • 58
    • 48
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Goat
    Host
    • 106
    • 17
    • 5
    • 1
    Rabbit
    Clonality
    • 114
    • 15
    Polyclonal
    Conjugate
    • 63
    • 15
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPOR antibody is un-conjugated
    Application
    • 89
    • 46
    • 24
    • 23
    • 22
    • 15
    • 14
    • 14
    • 11
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DHLGASLWPQ VGSLCLLLAG AAWAPPPNLP DPKFESKAAL LAARGPEELL
    Predicted Reactivity
    Cow: 85%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against EPOR. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human EPOR
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  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 508 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    EPOR (Erythropoietin Receptor (EPOR))
    Alternative Name
    EPOR (EPOR Products)
    Synonyms
    EPOR antibody, epor antibody, EPO-R antibody, erythropoietin receptor antibody, erythropoietin receptor L homeolog antibody, EPOR antibody, epor antibody, Epor antibody, epor.L antibody
    Background
    The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC138358, EPO-R
    Protein Interaction Partner: PIK3R1, SRC, MST1R, JAK2, SH2B2, STAT5A, CBL, CRKL, GRB2, UBC, SOCS2, PLCG1, INPP5D, CISH, NOSIP, ATXN2L, GAB2, GAB1, GRAP, STAT5B, SOCS3, MAPK3, IRS2, SHC1, PLCG2, SYK, KITLG, GNB2L1, MAPK1, PTPN6, PTPN11, KLK3, LYN, KIT, VAV1, GNAI1, CSF2RB, EPOR, EPO,
    Protein Size: 508
    Molecular Weight
    53 kDa
    Gene ID
    2057
    NCBI Accession
    NM_000121, NP_000112
    UniProt
    P19235
    Pathways
    JAK-STAT Signaling
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