WDR33 antibody (Middle Region)

Catalog No. ABIN2781910

Product Details anti-WDR33 Antibody

Target: WDR33 (WD Repeat Domain 33 (WDR33))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR33 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TKFVRTSTNK VKCPVFVVRW TPEGRRLVTG ASSGEFTLWN GLTFNFETIL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against WDR33. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WDR33

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 257 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-WDR33 antibody (ABIN2781910)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for WDR33

Target: WDR33 (WD Repeat Domain 33 (WDR33))

Alternative Name: WDR33 (WDR33 Products)

Synonyms: zgc:110570 antibody, WDR33 antibody, Wdr33 antibody, NET14 antibody, WDC146 antibody, 1110001N06Rik antibody, 2310011G05Rik antibody, 2810021O11Rik antibody, 8430413N20Rik antibody, WD repeat domain 33 antibody, pre-mRNA 3' end processing protein WDR33 antibody, wdr33 antibody, WDR33 antibody, Wdr33 antibody, LOC100548555 antibody

Background: WDR33 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: FLJ11294, WDC146, NET14
Protein Interaction Partner: SUMO1, WWOX, RPA3, RPA2, RPA1, BMI1, CLK2, CDK6, DYRK4, HDAC11, UBC, CDK4, MDC1, BARD1, ZNF622, FIP1L1, CPSF2, CPSF3, CPSF1, MED17, ISG15, HNRNPA1, ELAVL1, SMARCAD1, RBM48, ZBTB16, EEF1G, ZHX1, KAT7, UTP14A, GIT1, SH3GL3, PRMT1, TP53, TGFBR1, PFN2, RNPS1,
Protein Size: 257

Molecular Weight: 30 kDa

Gene ID: 55339

NCBI Accession: NM_001006623, NP_001006624

UniProt: Q6NUQ0