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HBEGF antibody (N-Term)

HBEGF Reactivity: Human, Mouse, Rat, Pig, Cow, Guinea Pig, Rabbit, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782149
  • Target See all HBEGF Antibodies
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Binding Specificity
    • 15
    • 15
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Pig, Cow, Guinea Pig, Rabbit, Dog
    Host
    • 69
    • 10
    Rabbit
    Clonality
    • 66
    • 12
    • 1
    Polyclonal
    Conjugate
    • 27
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HBEGF antibody is un-conjugated
    Application
    • 35
    • 29
    • 26
    • 15
    • 13
    • 11
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    FLAAVLSALV TGESLERLRR GLAAGTSNPD PPTVSTDQLL PLGGGRDRKV
    Predicted Reactivity
    Cow: 100%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against HBEGF. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human HBEGF
    Top Product
    Discover our top product HBEGF Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Alternative Name
    HBEGF (HBEGF Products)
    Synonyms
    hbegf antibody, zgc:165443 antibody, HBEGF antibody, zgc:175091 antibody, DTR antibody, DTS antibody, DTSF antibody, HEGFL antibody, Dtr antibody, GFHB antibody, Hb-egf antibody, Hegfl antibody, AW047313 antibody, Dts antibody, HB-EGF antibody, heparin-binding EGF-like growth factor b antibody, heparin binding EGF like growth factor antibody, Heparin-binding EGF-like growth factor antibody, heparin-binding EGF-like growth factor a antibody, heparin-binding EGF-like growth factor antibody, hbegfb antibody, HBEGF antibody, hbegf antibody, hbegfa antibody, Hbegf antibody
    Background
    HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.
    Alias Symbols: DTR, DTS, DTSF, HEGFL
    Protein Interaction Partner: Bag1, BCL6, ZBTB16, CD82, NRD1, LTBP3, ERBB4, MMP7, CD9, FBLN1, EGFR, HBEGF, CD44,
    Protein Size: 208
    Molecular Weight
    22 kDa
    Gene ID
    1839
    NCBI Accession
    NM_001945, NP_001936
    UniProt
    Q99075
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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