LTB antibody (C-Term)

Catalog No. ABIN2782174

Product Details anti-LTB Antibody

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Pig, Horse, Rabbit, Guinea Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PELLLEGAET VTPVLDPARR QGYGPLWYTS VGFGGLVQLR RGERVYVNIS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LTB

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LTB

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Alternative Name: LTB (LTB Products)

Synonyms: AI662801 antibody, LTbeta antibody, Tnfc antibody, Tnfsf3 antibody, p33 antibody, TNFC antibody, TNFSF3 antibody, LT-b antibody, LT-beta antibody, TNF-C antibody, lymphotoxin B antibody, lymphotoxin beta antibody, Ltb antibody, LTB antibody

Background: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
Protein Size: 244

Molecular Weight: 26 kDa

Gene ID: 4050

UniProt: Q06643

Pathways: NF-kappaB Signaling